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Manual article review is required for this article
Manual article review is required for this article
Of those Atgs, Beclin 1, the mammalian ortholog of yeast Atg6, interacts with class III PI3K (also named Vps34) and thus plays an essential position inside the initiation of autophagosome formation through autophagy7. Beclin 1 is the very first autophagy-similar tumor suppressor gene claimed Up to now, and it has been demonstrated to stimulate auto